Can’t open it by double clicking/right clicking. I have to autorun it every time. What is the reason for this?

All these symptoms mean your computer is definitely infected with a worm.
Please back up the data from all your hard drives and USB drives and reformat the entire computer. Download and update good antivirus andantispyware programs such as AVG Free and Spybot Search & Destroy, and then scan all your older data before copying it back to your computer.



OR
TRY USB disk security and use the repair registry function.It will restore Folder options, turn off button etc………………………………………..Try it.